South Africa tightened their grip on the second Test against England thanks to a third day of steady accumulation at Trent Bridge.
Dean Elgar, Hashim Amla and returning captain Faf du Plessis all brought up half-centuries, with the home attack forced to toil for their wickets before the Proteas declared on 343-9.
Alastair Cook had a first-ball lbw dismissal by Morne Morkel overturned on review as England began an improbable attempt at what would be a world-record chase of 474 and, even though he and Keaton Jennings nervily reached one without loss at the close, Joe Root's side are likely to head to The Oval at 1-1 in the four-match series.
After breezing to a 211-run win in his first Test in charge at Lord's, Root has become more attuned to the harsh realities of captaincy in the longest format in Nottingham, with a paltry first-innings effort of 205 leaving England chasing the game.
Opener Elgar and Amla resumed on 75 for one and set about methodically building upon their overnight lead of 205 on a morning of ragged frustration for their opponents.
Elgar, not always the easiest batsman on the eye, passed 50 with a thick outside edge off James Anderson and another nick off Stuart Broad fell safely in the following over.
Broad and England then offered up an error they could ill afford – appealing half-heartedly and neglecting to use a review when replays showed Amla feathered a delivery behind to Jonny Bairstow when on 25.
In Broad's next set of six, new-ball partner Anderson dropped a tough one-handed chance at gully after Elgar slashed at a wide one, but England were rewarded for their persistence with two wickets in as many overs before lunch.
Ben Stokes – who bustled in impressively for his 2-34 – unsettled Elgar with some short stuff and the left-hander appeared to pull out of his stroke as he lobbed a catch to square leg to depart for 80.
Anderson (2-45) was the catcher and he then encouraged the dangerous Quinton de Kock to edge behind.
Amla remained at lunch, having brought up his fifty with a six off Liam Dawson, as he did in the first innings, although the Hampshire all-rounder had South Africa's number three dismissed leg before on review, 13 shy of a century.
Dawson's fellow spinner Moeen Ali was ignored by Root until mid-afternoon but helped himself to 4-78 as South Africa belatedly looked to hit out after reaching tea on 236 for four.
Du Plessis crunched three through the covers off Moeen to raise his bat but saw partner Temba Bavuma continue his struggles against spin by lofting the Worcestershire man to Root at mid-off.
Anderson, Broad and Mark Wood all summoned probing but unrewarding spells with the second new ball before Stokes pinned Du Plessis in front for 63 with one that kept low.
Gary Ballance and Stuart Broad held fine catches as Chris Morris and Keshav Maharaj tried to slog Moeen with the declaration in sight.
Vernon Philander had more success in that regard during a breezy 42 that ended with a caught and bowled for Moeen, although his more decisive work is probably still to come with ball in hand alongside Morkel, who bowled with palpable menace during a gripping end to the day.
|Arsenal 4 West Ham 1: Wenger´s long farewell begins in style|
|Stoke City 1 Burnley 1: Potters pegged back again as relegation nears|
|N´Zonzi apologises for partying after Sevilla´s Copa humiliation|
|Khan chasing Brook, not world titles, after spectacular comeback|
|Kaizer Chiefs ´worried about safety of players´ as coach quits after rioting|
|Elneny injury sparks World Cup fear|
|Arsenal aiming to give Wenger the perfect send off - Mertesacker|
|Chelsea v Southampton: Giroud wins Wembley nod over Morata|
|Don´t go to China, come to Betis! - Setien lauds Barcelona legend Iniesta|
|Argentina midfielder Biglia suffers ´severe´ back injury in Milan defeat|
|Departing Wenger hints at end-of-season reveal amid reports of sacking|
|Farah sets new British record as Kipchoge wins London Marathon|
|Neymar walking without crutches|
|Ozil ill, Aubameyang benched as Arsenal target momentum ahead of Atletico|
|I make the decisions - Sweden coach wants Ibrahimovic talks on World Cup|
|Investment not necessary for United to challenge City – Lukaku|
|So close, but so far away – Vorm laments another Spurs failure|
|Melbourne Victory 2 Adelaide United 1: Berisha stunner seals last-four spot|
|Sharks upset Panthers as Eels finally get off the mark|
|Lopes: A return to Man City? My present is Monaco but the future belongs to God|
|Jaguares catch out Brumbies in Canberra|
|Montella urges Sevilla to use Copa setback as motivation|
|Zheng topples Wang in Zhengzhou final|
|Rakitic desperate for Iniesta stay|
|Jardim one of the best in the world – Lopes praises Monaco boss amid interest|
|Napoli refusing to give up on Scudetto dream|
|It´s a good time for Iniesta to leave Barca, says father|
|Athletics´ Manaea no-hits Red Sox, Darvish struggles once again|
|Pelicans reach second round, 76ers take 3-1 lead and T-Wolves down Rockets|
|MLS Review: Five-star LAFC, Dynamo headline goal frenzy as Atlanta silence Ibra´s Galaxy|
|Busch pulls away to claim third successive NASCAR win|
|Sanchez hails legendary Wenger ahead of Arsenal exit|
|Valverde: Nothing behind Iniesta substitution amid growing CSL links|
|White Sox´s Farquhar in critical condition after brain haemorrhage|
|Cubs place Ben Zobrist on 10-day DL|
|Hoffenheim boss Nagelsmann dismisses Arsenal and Chelsea links|
|Johnson, Landry tied for Texas lead as Mullinax sets course record|
|Gattuso, Mirabelli apologise to Milan fans after ´embarrassing´ Benevento loss|
|Marquez to start fourth after being stripped of Austin pole|
|Iniesta to make decision on his future public ´this week´|
|United want to win everything next year, says Wembley hero Sanchez|
|Cardiff edge Forest to boost promotion push|
|Bartomeu confirms Iniesta has an ´offer´ amid Chinese Super League reports|
|Messi second player to score in five Copa finals|
|Khan makes up for lost time with 40-second Lo Greco knockout|
|Mourinho challenges Alexis after Wembley star turn|
|Vieira ready for Arsenal job, says Guardiola|
|FA Cup win would represent successful season - Conte|
|Guardiola: I want Manchester City to be a Premier League machine|
|Marquez crashes before taking controversial pole in Austin|
|Sevilla 0 Barcelona 5: Suarez and Messi lead crushing Copa final win|
|Defending champion Selby dumped out in first round|
|AC Milan 0 Benevento 1: Rossoneri suffer again as bottom side stave off relegation...for now|
|Ulster stay alive in dramatic fashion as Bellini sparkles for Zebre|
|Semi-final pain for frustrated Kane|
|London stay was crucial to FA Cup Wembley win - Mourinho|
|Pochettino: Spurs need four more years – with me or another|
|Kaepernick honoured with Amnesty International award|
|He has not delivered optimal performances - Stoger explains Schmelzer omission|
|Kvitova and Pliskova put Czechs in control|
|Modric open to Ibrahimovic union in MLS|
|Spurs can´t keep doing this – Alli|
|Bulls keep Rebels waiting for South Africa win, Sharks beat Stormers|
|Heynckes highlights importance of ´psychology´ before Real Madrid clash|
|United are about winning titles and playing finals, says happy Herrera|
|Pogba and United the comeback kings again|
|Destructive De Villiers demolishes Daredevils|
|Giroud thanks Wenger for making his ´dream come true´|
|Borussia Dortmund 4 Bayer Leverkusen 0: Reus and Sancho star as Stoger´s side go third|
|Manchester United 2 Tottenham 1: Sanchez and Herrera seal comeback to book FA Cup final spot|