Former top draft picks Jared Goff and Carson Wentz stepped up to lead the Los Angeles Rams and Philadelphia Eagles respectively to NFL wins.
The Rams traded up in the 2016 draft to get the number one pick and chose Goff, who struggled in seven games as a rookie.
The Eagles traded up to select Wentz second, and he had a typical up-and-down rookie campaign.
But both players showed why they were so highly touted a year ago, racking up big numbers in leading their teams to victory on Sunday.
Wentz set the tone early in Philly's game against the Washington Redskins, scrambling around in the pocket like vintage Randall Cunningham to buy time to find Nelson Agholor for a 58-yard touchdown.
Wentz completed 26 of 39 passes for the game, with two touchdowns and a pick in the Eagles' 30-17 victory.
The Rams hammered the Indianapolis Colts 46-9, and while the defense keyed the win with two pick-sixes and a safety, Goff was extremely efficient with 21 of 29 passing, for 306 yards and a touchdown.
RYAN THROWS 88-YARD TD
Matt Ryan threw an 88-yard touchdown to tight end Austin Hooper.
How many times will we see Aaron Rodgers to Jordy Nelson for a score this season?
San Francisco safety Jaquiski Tartt broke up a would-be TD pass from Cam Newton to Kelvin Benjamin with a leaping interception.
Browns fans, hide your eyes: The Steelers recovered a blocked punt for a TD after their first defensive series.
What a way to start the regular season.— Pittsburgh Steelers (@steelers) September 10, 2017
PIT 7 | CLE 0 pic.twitter.com/EwpwJ9dftt
Dak Prescott picked up where he left off last season.
Lamarcus Joyner had a pick-six for the Rams.
WITTEN, FOURNETTE SET NEW MARKS
Jason Witten passed Michael Irvin to become the Cowboys' all-time leader in receiving yards. Irvin finished his career with 11,904 yards. Witten, who caught seven passes for 59 yards and a touchdown in a win over the Giants, now has 11,947 career receiving yards.
Jaguars' Leonard Fournette rushed for 100 yards and a touchdown in a 29-7 win over the Texans, becoming the first rookie in team history to hit 100 yards in his debut.
WATT SHRUGS OFF SCARE
"I messed up my finger a little bit, but other than that my body felt fine. Just busted the bone through the skin. Nothing bad." – Texans defensive star J.J. Watt, shrugging off a finger injury that would probably scare some people.
"I mean, we got our arses kicked. Credit the 49ers and coach [Sean] McVay." – coach Chuck Pagano, praising the team that beat the Colts on Sunday … except the Colts lost to the Rams.
"I thought that Tom hung in there and played tough. We had a hard time protecting him, so I made the decision to go to Deshaun." – Texans coach Bill O'Brien, on benching starting QB Tom Savage in favour of rookie Deshaun Watson in the second half of their loss to the Jaguars.
"Most of the time I'm thinking about my wife in my wildest dreams." – Jaguars coach Doug Marrone on if the week one win met his wildest dreams.
Buffalo Bills 21-12 New York Jets
Philadelphia Eagles 30-17 Washington Redskins
Oakland Raiders 26-16 Tennessee Titans
Jacksonville Jaguars 29-7 Houston Texans
Detroit Lions 35-23 Arizona Cardinals
Pittsburgh Steelers 21-18 Cleveland Browns
Atlanta Falcons 23-17 Chicago Bears
Baltimore Ravens 20-0 Cincinnati Bengals
Los Angeles Rams 46-9 Indianapolis Colts
Carolina Panthers 23-3 San Francisco 49ers
Green Bay Packers 17-9 Seattle Seahawks
Dallas Cowboys 19-3 New York Giants
|Race to Dubai winner Fleetwood hails ´biggest day of my career´|
|Dutch Grand Prix a ´realistic´ prospect from 2020|
|Sampdoria 3 Juventus 2: Champions slip further off the pace after thriller|
|Coleman confirmed as Sunderland boss|
|I was just injured - Belgium´s Nainggolan blasts ´stupid´ claims of feigned ailment|
|Leeds United 2 Middlesbrough 1: Losing streak snapped to ease pressure on Christiansen|
|Ioane and Romano to miss All Blacks´ Wales clash|
|One punch only! Tete retains world title with 11-second knockout|
|Hughes backs Giggs for Wales job|
|Bennett: Social media clip prompted Brown withdrawal|
|Memorable Ashes Moments: Anderson and Panesar defy Australia in Cardiff|
|Madrid confirm Ramos´ broken nose after derby clash|
|Kane wants to retire with Tottenham|
|Mourinho: Man United lacked balance with attacking line-up|
|Fleetwood wins Race to Dubai after Rose wilts, Rahm claims tournament win|
|Pastore not considering PSG exit to help World Cup chances|
|Wenger, Ozil & Sanchez uncertainty affecting Arsenal, says Seaman|
|Dhawan, Rahul lead India revival in Kolkata|
|Silva not surprised by Chelsea, Spurs interest in Richarlison|
|Ancelotti, Conte, Allegri on shortlist to replace Ventura|
|Bencic doubles up with Taipei title|
|Perth Glory 0 Melbourne Victory 2: Visitors claim first A-League win of season|
|Bayliss calls for A-team matches on Ashes tours|
|Smith will bowl in the Ashes, says Lehmann|
|Marcelo unaware of Ramos-Ronaldo rift at Real Madrid|
|England book Tonga semi with PNG win|
|Celtics win 15th straight, 76ers in collapse against Warriors|
|Lehmann tells Australia: Get behind the Ashes team|
|Goffin revels in career-best win after upstaging Federer|
|Neymar will take PSG´s next penalty - Cavani|
|Ranieri would consider coaching Italy|
|It´s been an amazing year - Federer signs off for 2017 after London exit|
|Postecoglou set for decision on Socceroos future|
|Celtics coach Stevens wants more despite 14-game streak|
|Kerr: What Embiid did against the Lakers was terrifying|
|Cook extends lead at RSM Classic|
|Frampton beats Garcia by unanimous decision in front of Canelo|
|Championship Review: Millwall deny sloppy Sunderland, Wolves back on top|
|Simeone rallies around under-fire Griezmann|
|Hogg and Barclay ´gutted´ to let All Blacks escape|
|It´s a growth process - Montella optimistic despite Napoli loss|
|Spalletti happy at Inter, tips Ancelotti for Italy job|
|Sarri defends sacked Ventura over Insigne´s Italy snub|
|Los Blank-os! Misfiring Real Madrid break new ground under Zidane|
|Zidane upbeat despite derby stalemate|
|Zidane unsure on Ramos absence with suspected broken nose|
|Mind the gap! Real Madrid must make history to retain LaLiga title|
|Dimitrov denies Sock to book Goffin showdown|
|Springboks gain measure of revenge over 2023 RWC hosts France|
|Alonso fuels Le Mans talk with WEC rookie test|
|Napoli 2 AC Milan 1: Insigne stars after Italy snub as leaders move four points clear|
|Atletico Madrid 0 Real Madrid 0: Defences dominate in historic derby|
|Wasps sting Falcons, Warriors off the mark|
|Montpellier take charge of Top 14 as Lyon slip up|
|Pjaca scores winner for Juventus Primavera on return from injury|
|Jones bristles at suggestion England ´got lucky´|
|Lions don´t recover like humans! - Ibrahimovic and Pogba thrilled to be back|
|Pogba was different class - Mourinho praises midfielder after impressive comeback|
|Competition is good – PSG boss Emery explains benching Mbappe|
|Klopp apologises after Moreno misses birth of child|
|Experimental Ireland XV survives Fiji scare|
|Cheika makes no excuses after controversial calls hurt Australia|
|Valiant Scotland fall short against clinical All Blacks|
|Manchester United 4 Newcastle United 1: Pogba shines as Ibrahimovic makes his return|
|Hodgson accuses Niasse of diving to win Everton penalty|
|´Why not?´ - Hazard believes Chelsea can catch City|
|Roma 2 Lazio 1: Nainggolan stunner proves decisive|
|Bournemouth hat-trick hero Wilson: I need to be selfish|
|Valverde admits scoreline in Leganes win was ´excessive´|
|Pulis leaves uncertain future to West Brom board|